Psychologist Alan Gregory befriends a suicidal fifteen-year-old girl and her ill little sister, and when a high-level associate of the HMO that denied the child treatment with an experimental drug is murdered, he realizes that his patient is somehow involved.

Dr. Alan Gregory confronts the case of a man who, having survived a near-fatal accident, makes an agreement with a shadowy organization that ends the lives of clients who do not want to be a burden in the event of dire illnesses or injuries.

After the shocking developments in Dry Ice, Colorado psychologist Alan Gregory is struggling to deal with his newly adopted son and repair his shaky, though generally improving, marriage. But then Alan's ex-wife, Merideth, reappears, seeking help she feels only Alan can give. Suddenly Alan is pulled into a mystery that reaches back years to a camping trip at the Grand Canyon involving Merideth's fiance and five friends whose lives were changed forever...

After one of their dinner party guests wakes up the next morning with no memory beyond getting ready for bed, Alan Gregory and his deputy district attorney wife, Lauren, join with detective Sam Purdy in an investigation that turns grim once one of the witnesses is murdered.