En route from New York City to Hollywood for a drag queen beauty pageant, Noxeema, Vida and Chi Chi are stranded in a tiny Midwestern town when their 1967 Cadillac breaks down. When their glitz and glamour wake up the sleepy local citizens, the stage is set for an outrageously funny weekend.

During their summer vacation, Danny Zuko and Sandy Olsson meet at a beach. Sandy enrolls at Rydell High School, where Danny is a student. Sandy's new friend Frenchy is a member of the schoolgirl clique 'The Pink Ladies.' Danny is the leader of the 'The T-Birds' gang. Kenickie is his second-in-command. Neither Danny or Sandy know they are attending the same school. The Pink Ladies decide to reunite Danny and Sandy, but Danny wants to protect his cool...